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Article

Nitric oxide, an autocrine regulator of wound fibroblast synthetic function.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 1997

Schäffer M R, Efron P A, Thornton F J, Klingel K, Gross S S, Barbul A

Abstract excerpt

Nitric oxide (NO) is synthesized in wounds, but its exact role and cellular source are not known. Wound fibroblasts (WF) are phenotypically characterized by increased collagen synthesis and contractility. We hypothesized that WF may be also phenotypically altered during wound healing to synthesize NO. WF were isolated from polyvinyl alcohol sponges implanted in male Lewis rats and harvested 10 days later....

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PMID: 9036987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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