Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of fibroblast-induced collagen gel contraction by interleukin-1beta.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Jul 1998

Irwin C R, Myrillas T, Smyth M, Doogan J, Rice C, Schor S L

Abstract excerpt

Fibroblasts incorporated within collagen gels induce a cell-mediated contraction of the gel to form a three-dimensional, tissue-like structure by a mechanism thought to mimic wound contraction in vivo. In this study a gel contraction model was used to investigate the ability of fibroblasts derived from adult gingiva, adult skin and fetal skin to organise a collagen matrix. In addition the effects of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to Collagen

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibroblasts

Share to Interleukin-1

Share to Phenotype

Share to Transforming Growth Factor beta

Source

Identifiers

PMID: 9707277
DOI: 10.1111/j.1600-0714.1998.tb01952.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of fibroblast-induced collagen gel contraction by interleukin-1beta.PMID 9707277Read ↗

A comparison of the ability of intra-oral and extra-oral fibroblasts to stimulate extracellular matrix reorganization in a model of wound contraction.Semantic proximity Read ↗

Human Gingival Fibroblasts Display a Non-Fibrotic Phenotype Distinct from Skin Fibroblasts in Three-Dimensional CulturesSemantic proximity Read ↗

Phenotypic differences between oral and skin fibroblasts in wound contraction and growth factor expression.Semantic proximity Read ↗

Fetal dermal fibroblasts retain a hyperactive migratory and contractile phenotype under 2-and 3-dimensional constraints compared to normal adult fibroblasts.Semantic proximity Read ↗

An investigation of preferential fibroblast wound repopulation using a novel in vitro wound model.Semantic proximity Read ↗

Differential expression and regulation of extracellular matrix‐associated genes in fetal and neonatal fibroblastsSemantic proximity Read ↗

How do fibroblasts interact with the extracellular matrix in wound contraction?Semantic proximity Read ↗

Construction of large area organotypical cultures of oral mucosa and skin.Semantic proximity Read ↗

In vitro study of the impact of mechanical tension on the dermal fibroblast phenotype in the context of skin wound healing.Semantic proximity Read ↗

Fibroblasts in mechanically stressed collagen lattices assume a "synthetic" phenotype.Semantic proximity Read ↗

Fibroblast biology in three-dimensional collagen matrices.Semantic proximity Read ↗

Mechanical tension increases CCN2/CTGF expression and proliferation in gingival fibroblasts via a TGFβ-dependent mechanism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.