Article
Long-term effect of PROLI/NO on cellular proliferation and phenotype after arterial injury.
Free radical biology & medicine - 1 Jan 2016
Bahnson Edward S M, Vavra Ashley K, Flynn Megan E, Vercammen Janet M, Jiang Qun, Schwartz Amanda R, Kibbe Melina R
Abstract excerpt
Vascular interventions are associated with high failure rates from restenosis secondary to negative remodeling and neointimal hyperplasia. Periadventitial delivery of nitric oxide (NO) inhibits neointimal hyperplasia, preserving lumen patency. With the development of new localized delivery vehicles, NO-based therapies remain a promising therapeutic avenue for the prevention of restenosis. While the time course of...
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