Article
Induction of hapten-specific tolerance of human CD8+ urushiol (poison ivy)-reactive T lymphocytes.
The Journal of investigative dermatology - 1 Mar 1997
Kalish R S, Wood J A
Abstract excerpt
The interaction of CD28 with B7 molecules (CD80 or CD86) is an essential second signal for both the activation of CD4+ T cells through the T-cell receptor and the prevention of anergy. We studied the requirement of hapten-specific human CD8+ cells for CD28 co-stimulation in recognition of hapten, and anergy induction. Urushiol, the immunogenic hapten of poison ivy (Toxicodendron radicans), elicits a predominantly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
