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Article

Constitutive expression in gal7 mutants of Kluyveromyces lactis is due to internal production of galactose as an inducer of the Gal/Lac regulon.

Molecular and cellular biology - 1 Mar 1997

Cardinali G, Vollenbroich V, Jeon M S, de Graaf A A, Hollenberg C P

Abstract excerpt

The induction process of the galactose regulon has been intensively studied, but until now the nature of the inducer has remained unknown. We have analyzed a delta gal7 mutant of the yeast Kluyveromyces lactis, which lacks the galactotransferase activity and is able to express the genes of the Gal/Lac regulon also in the absence of galactose. We found that this expression is semiconstitutive and undergoes a...

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Identifiers

PMID: 9032299
DOI: 10.1128/MCB.17.3.1722
PMCID: PMC231897

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Source receipt: pubmed, retrieved 7 Sept 2026.

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