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Article

Restricted sugar uptake by sugar-induced internalization of the yeast lactose/galactose permease Lac12.

FEMS yeast research - 1 May 2011

Rigamonte Tatiana A, Silveira Wendel B, Fietto Luciano G, Castro Ieso M, Breunig Karin D, Passos Flávia M L

Abstract excerpt

Kluyveromyces lactis Lac12 permease mediates lactose and low-affinity galactose transports. In this study we investigated the effects of carbon sources on internalization of Lac12 using a LAC12-GFP fusion construct. When galactose- or lactose-grown cells are shifted to a fresh sugar medium, Lac12-GFP is removed from the plasma membrane and is localized intracellularly. Surprisingly, either galactose or lactose in...

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Identifiers

PMID: 21205157
DOI: 10.1111/j.1567-1364.2010.00709.x

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