Article
The molecular basis of Hb H disease in Turkey.
Hemoglobin - 1 Jan 1997
Oner C, Gürgey A, Oner R, Balkan H, Gümrük F, Baysal E, Altay C
Abstract excerpt
A total of 25 unrelated Hb H patients were studied at the DNA level. Ten different genotypes were found to be responsible for the disease. The most prevalent alpha-thalassemia-2 determinant was the alpha alpha/-alpha (3.7) kb deletion (56%) which was followed by a nondeletional type of alpha-thalassemia, namely the pentanucleotide deletion in the 5' first intervening sequence splice junction [alpha(-5nt) alpha]...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.