The molecular basis of Hb H disease in Turkey.

doi:10.3109/03630269708997509

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Article

The molecular basis of Hb H disease in Turkey.

Hemoglobin - 1 Jan 1997

Oner C, Gürgey A, Oner R, Balkan H, Gümrük F, Baysal E, Altay C

Abstract excerpt

A total of 25 unrelated Hb H patients were studied at the DNA level. Ten different genotypes were found to be responsible for the disease. The most prevalent alpha-thalassemia-2 determinant was the alpha alpha/-alpha (3.7) kb deletion (56%) which was followed by a nondeletional type of alpha-thal...

Topics

Adolescent
Adult
Child
Child, Preschool
Female
Genotype
Hematologic Tests
Hemoglobin H
Humans
Male
Phenotype
Turkey

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