Article
Molecular basis of Hb H disease in southwest Iran.
Hemoglobin - 1 Jan 2005
Yavarian Majid, Karimi Mehran, Zorai Amine, Harteveld Cornelis L, Giordano Piero C
Abstract excerpt
Although alpha0-thalassemia (thal) defects are not very frequent in the Iranian population, Hb H disease does occur in the country. We have analyzed the alpha gene cluster of 13 patients showing the presence of Hb H to establish the molecular background of this disease in southwest Iran (Shiraz and Hormozgan provinces). Using gap-polymerase chain reaction (gap-PCR) and direct DNA sequencing we have found the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.