Article
Proliferating cells in the primary spongiosa express osteoblastic phenotype in vitro.
Bone - 1 Feb 1997
Onyia J E, Miller B, Hulman J, Liang J, Galvin R, Frolik C, Chandrasekhar S, Harvey A K, Bidwell J, Herring J, Hock J M
Abstract excerpt
We have shown that intermittent parathyroid hormone (PTH) treatment targets proliferating cells in the primary spongiosa of trabecular bone of young rats, resulting in an increased number of osteoblasts. To further characterize these proliferating osteoprogenitor cells, bromodeoxyuridine (BrdUrd)...
Topics
- Animals
- Blood Physiological Phenomena
- Bone and Bones
- Bromodeoxyuridine
- Cattle
- Cell Division
- DNA
- Dexamethasone
- Humans
- Immunohistochemistry
- Male
- Nucleic Acid Synthesis Inhibitors
- Osteoblasts
- Parathyroid Hormone
- Phenotype
- Platelet-Derived Growth Factor