Article
Quiescent Bone Lining Cells Are a Major Source of Osteoblasts During Adulthood.
Stem cells (Dayton, Ohio) - 1 Dec 2016
Matic Igor, Matthews Brya G, Wang Xi, Dyment Nathaniel A, Worthley Daniel L, Rowe David W, Grcevic Danka, Kalajzic Ivo
Abstract excerpt
The in vivo origin of bone-producing osteoblasts is not fully defined. Skeletal stem cells, a population of mesenchymal stem cells resident in the bone marrow compartment, are thought to act as osteoprogenitors during growth and adulthood. Quiescent bone lining cells (BLCs) have been suggested as a population capable of activation into mature osteoblasts. These cells were defined by location and their morphology...
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