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Article

A Novel Transgenic Mouse Model to Study the Osteoblast Lineage <i>in Vivo</i>

1 Nov 2007

Abstract excerpt

Over the past few decades, osteoblast differentiation has been studied extensively in a variety of culture systems and findings from these experiments have shaped our understanding of the bone-forming cell lineage. However, in vitro assays are bound by intrinsic limitations and are unable to effectively mirror many aspects related to osteoblasts in vivo, including their origin, destiny, and life span. Therefore,...

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PMID: 18083926
DOI: 10.1196/annals.1402.060

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