Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA-DQ (alpha 1*0501, beta 1*02) or the HLA-DQ (alpha 1*03, beta 1*0302) heterodimers.

doi:10.1111/j.1399-0039.1997.tb02706.x

Article

Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA-DQ (alpha 10501, beta 102) or the HLA-DQ (alpha 103, beta 10302) heterodimers.

Tissue antigens - 1 Jan 1997

Spurkland A, Ingvarsson G, Falk E S, Knutsen I, Sollid L M, Thorsby E

Abstract excerpt

HLA-DRB1,-DQA1, and -DQB1 genomic typing of 50 patients with dermatitis herpetiformis and of 290 healthy blood donors was performed. Genes encoding the DQ (alpha 1*0501, beta 1*02) heterodimer were carried by 43 (86%) of the patients and 72 (25%) of the controls. Of the remaining seven patients s...

Topics

Case-Control Studies
Celiac Disease
Dermatitis Herpetiformis
Genotype
HLA-DQ Antigens
HLA-DQ alpha-Chains
HLA-DQ beta-Chains
HLA-DR Antigens
HLA-DRB1 Chains
Haplotypes
Humans

Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA-DQ (alpha 1*0501, beta 1*02) or the HLA-DQ (alpha 1*03, beta 1*0302) heterodimers.

Abstract excerpt

Topics

Discuss the evidence

Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA-DQ (alpha 10501, beta 102) or the HLA-DQ (alpha 103, beta 10302) heterodimers.