Article
HLA association with dermatitis herpetiformis is accounted for by a cis or transassociated DQ heterodimer.
Gut - 1 May 1991
Hall M A, Lanchbury J S, Bolsover W J, Welsh K I, Ciclitira P J
Abstract excerpt
HLA-DR, DQ, and DP restriction fragment genotyping was undertaken in 23 dermatitis herpetiformis patients and 53 healthy control subjects. HLA-DQw2 was present in 100% of patients with dermatitis herpetiformis (23 of 23) versus 40% of control subjects (21 of 53). Significant secondary association...
Topics
- Celiac Disease
- Dermatitis Herpetiformis
- Disease Susceptibility
- Genotype
- HLA-DP Antigens
- HLA-DQ Antigens
- HLA-DR Antigens
- HLA-DR3 Antigen
- Humans
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length