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Article

HLA class II region genes and susceptibility to dermatitis herpetiformis: DPB1 and TAP2 associations are secondary to those of the DQ subregion.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 1996

Hall M A, Lanchbury J S, Ciclitira P J

Abstract excerpt

Classical dermatitis herpetiformis (DH) is associated with similar HLA class I, II and III polymorphisms to coeliac disease (CD). The two diseases share distinctive pathological changes to the small intestinal mucosa which reverse on withdrawal of dietary gluten. In order to determine the locus primarily associated with DH, and to examine whether there is a common genetic link predisposing to the enteropathy seen...

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Source

Identifiers

PMID: 8858285
DOI: 10.1111/j.1744-313x.1996.tb00124.x

Genes

TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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HLA class II region genes and susceptibility to dermatitis herpetiformis: DPB1 and TAP2 associations are secondary to those of the DQ subregion.PMID 8858285Read ↗

HLA association with dermatitis herpetiformis is accounted for by a cis or transassociated DQ heterodimer.Semantic proximity Read ↗

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Immunoglobulin and HLA-DP genes contribute to the susceptibility to juvenile dermatitis herpetiformis.Semantic proximity Read ↗

An HLA class II region restriction fragment length polymorphism (RFLP) in patients with dermatitis herpetiformis: association with HLA-DP phenotype.Semantic proximity Read ↗

Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA-DQ (alpha 1*0501, beta 1*02) or the HLA-DQ (alpha 1*03, beta 1*0302) heterodimers.Semantic proximity Read ↗

Dermatitis herpetiformis. Part I. Epidemiology, pathogenesis, and clinical presentation.Semantic proximity Read ↗

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