Article
HLA class II region genes and susceptibility to dermatitis herpetiformis: DPB1 and TAP2 associations are secondary to those of the DQ subregion.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 1996
Hall M A, Lanchbury J S, Ciclitira P J
Abstract excerpt
Classical dermatitis herpetiformis (DH) is associated with similar HLA class I, II and III polymorphisms to coeliac disease (CD). The two diseases share distinctive pathological changes to the small intestinal mucosa which reverse on withdrawal of dietary gluten. In order to determine the locus p...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Adult
- Alleles
- Dermatitis Herpetiformis
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-DP Antigens
- HLA-DP beta-Chains
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- Humans
- Polymorphism, Genetic
