Article
A conserved glutamate residue, Glu-257, is important for substrate binding and transport by the Escherichia coli mannitol permease.
Journal of bacteriology - 1 Feb 1997
Saraceni-Richards C A, Jacobson G R
Abstract excerpt
The mannitol permease, or D-mannitol-specific enzyme II of the phosphoenolpyruvate-dependent carbohydrate phosphotransferase system (PTS) of Escherichia coli, both transports and phosphorylates its substrate. Previous analyses of the amino acid sequences of PTS permeases specific for various carbohydrates in different species of bacteria revealed several regions of similarity. The most highly conserved region...
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