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Article

Molecular Modification Enhances Xylose Uptake by the Sugar Transporter KM_SUT5 of Kluyveromyces marxianus.

International journal of molecular sciences - 30 Jul 2024

Luo Xiuyuan, Tao Xi, Ran Guangyao, Deng Yuanzhen, Wang Huanyuan, Tan Liyan, Pang Zongwen

Abstract excerpt

This research cloned and expressed the sugar transporter gene KM_SUT5 from Kluyveromyces marxianus GX-UN120, which displayed remarkable sugar transportation capabilities, including pentose sugars. To investigate the impact of point mutations on xylose transport capacity, we selected four sites, predicted the suitable amino acid sites by molecular docking, and altered their codons to construct the corresponding...

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Identifiers

PMID: 39125891
DOI: 10.3390/ijms25158322
PMCID: PMC11312716

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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