Article
Saccharomyces cerevisiae exhibits a yAP-1-mediated adaptive response to malondialdehyde.
Journal of bacteriology - 1 Feb 1997
Turton H E, Dawes I W, Grant C M
Abstract excerpt
Malondialdehyde (MDA) is a highly reactive aldehyde generally formed as a consequence of lipid peroxidation. MDA has been inferred to have mutagenic and cytotoxic roles and possibly to be a participant in the onset of atherosclerosis. Wild-type Saccharomyces cerevisiae acquires resistance to a lethal dose (5 mM) of MDA following prior exposure to a nonlethal concentration (1 mM). This response was completely...
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