Article
Kinetics of arylamine N-acetyltransferase in tissues from human breast cancer.
Cancer letters - 1 Jan 1997
Lee J H, Chung J G, Lai J M, Levy G N, Weber W W
Abstract excerpt
N-Acetyltransferase activity and Michaelis-Menten kinetic constants were determined in cancerous and non-cancerous breast tissues from 30 female patients with breast cancer. The results derived from tissue cytosol showed that 12 rapid, ten intermediate and eight slow acetylators based on p-aminobenzoic acid and 2-aminofluorene for substrates. The mean apparent Km values for the monomorphic substrate...
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