Deletion mapping of chromosome 4 in head and neck squamous cell carcinoma.

doi:10.1038/sj.onc.1200836

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Article

Deletion mapping of chromosome 4 in head and neck squamous cell carcinoma.

Oncogene - 23 Jan 1997

Pershouse M A, El-Naggar A K, Hurr K, Lin H, Yung W K, Steck P A

Abstract excerpt

Genomic deletions involving chromosome 4 have recently been implicated in several human cancers. To identify and characterize genetic events associated with the development of head and neck squamous cell carcinoma (HNSCC), a fine mapping of allelic losses associated with chromosome 4 was performed on DNA isolated from 27 matched primary tumor specimens and normal tissues. Loss of heterozygosity (LOH) of at least...

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PMID: 9018123
DOI: 10.1038/sj.onc.1200836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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