Article
Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster.
Genetics - 1 Sept 1990
Jones R S, Gelbart W M
Abstract excerpt
The Enhancer of zeste [E(z)] locus of Drosophila melanogaster is implicated in multiple examples of gene regulation during development. First identified as dominant gain-of-function modifiers of the zeste1-white (z-w) interaction, mutant E(z) alleles also produce homeotic transformations. Reduction of E(z)+ activity leads to both suppression of the z-w interaction and ectopic expression of segment identity genes...
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