Article
The Drosophila Polycomb-group gene Enhancer of zeste contains a region with sequence similarity to trithorax.
Molecular and cellular biology - 1 Oct 1993
Jones R S, Gelbart W M
Abstract excerpt
As is typical of Polycomb-group loci, the Enhancer of zeste [E(z)] gene negatively regulates the segment identity genes of the Antennapedia (ANT-C) and Bithorax (BX-C) gene complexes. A second class of loci, collectively known as the trithorax group, plays an antagonistic role as positive regulators of the ANT-C and BX-C genes. Molecular analysis of the E(z) gene predicts a 760-amino-acid protein product. A...
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