Article
The Drosophila trithorax gene encodes a chromosomal protein and directly regulates the region-specific homeotic gene fork head.
Genes & development - 15 Oct 1994
Kuzin B, Tillib S, Sedkov Y, Mizrokhi L, Mazo A
Abstract excerpt
The activity of the Drosophila gene trithorax is required to maintain the proper spatial pattern of expression of multiple homeotic genes of the Bithorax and Antennapedia complexes, trithorax encodes two large protein isoforms of > 400 kD. We have detected its products at 16 discrete sites on lar...
Topics
- Animals
- Binding Sites
- Chromosomes
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Female
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Genes, Insect
- Immunohistochemistry
- Larva
- Male
- Mutation
- Protein Processing, Post-Translational
- Transcription Factors