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Association between possession of ExoU and antibiotic resistance in Pseudomonas aeruginosa

28 Sept 2018

Abstract excerpt

Virulent strains of Pseudomonas aeruginosa are often associated with an acquired cytotoxic protein, exoenzyme U (ExoU) that rapidly destroys the cell membranes of host cells by its phospholipase activity. Strains possessing the exoU gene are predominant in eye infections and are more resistant to antibiotics. Thus, it is essential to understand treatment options for these strains. Here, we have investigated the...

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PMID: 30265709
DOI: 10.1371/journal.pone.0204936

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