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Article

Cytotoxic clinical isolates of Pseudomonas aeruginosa identified during the Steroids for Corneal Ulcers Trial show elevated resistance to fluoroquinolones.

BMC ophthalmology - 24 Apr 2014

Borkar Durga S, Acharya Nisha R, Leong Chelsia, Lalitha Prajna, Srinivasan Muthiah, Oldenburg Catherine E, Cevallos Vicky, Lietman Thomas M, Evans David J, Fleiszig Suzanne M J

Abstract excerpt

BACKGROUND: To determine the relationship between type three secretion genotype and fluoroquinolone resistance for P. aeruginosa strains isolated from microbial keratitis during the Steroids for Corneal Ulcers Trial (SCUT) and for two laboratory strains, PA103 and PAO1. METHODS: Confirmed P. aeruginosa isolates from the SCUT were divided into exoU(+) or exoU(-). The exoU(+) strains contained the gene encoding...

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Identifiers

PMID: 24761794
DOI: 10.1186/1471-2415-14-54
PMCID: PMC4008435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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