Article
The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio.
Development (Cambridge, England) - 1 Dec 1996
Haffter P, Granato M, Brand M, Mullins M C, Hammerschmidt M, Kane D A, Odenthal J, van Eeden F J, Jiang Y J, Heisenberg C P, Kelsh R N, Furutani-Seiki M, Vogelsang E, Beuchle D, Schach U, Fabian C, Nüsslein-Volhard C
Abstract excerpt
In a large-scale screen, we isolated mutants displaying a specific visible phenotype in embryos or early larvae of the zebrafish, Danio rerio. Males were mutagenized with ethylnitrosourea (ENU) and F2 families of single pair matings between sibling F1 fish, heterozygous for a mutagenized genome, were raised. Egg lays were obtained from several crosses between F2 siblings, resulting in scoring of 3857 mutagenized...
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