Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of genotoxicity of nitrile fragrance ingredients using in vitro and in vivo assays.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Sept 2013

Bhatia S P, Politano V T, Api A M

Abstract excerpt

Genotoxicity studies were conducted on a group of 8 fragrance ingredients that belong to the nitrile family. These nitriles are widely used in consumer products however there is very limited data in the literature regarding the genotoxicity of these nitriles. The 8 nitriles were assessed for genotoxicity using an Ames test, in vitro chromosome aberration test or in vitro micronucleus test. The positive results...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cricetulus
Share to Cricetinae

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred Strains

Share to Micronucleus Tests

Share to Mutagenicity Tests

Share to Nitriles

Share to Odorants

Share to Salmonella typhimurium

Source

Identifiers

PMID: 23643699
DOI: 10.1016/j.fct.2013.04.040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of genotoxicity of nitrile fragrance ingredients using in vitro and in vivo assays.PMID 23643699Read ↗

Genotoxicity guidelines recommended by International Conference of Harmonization (ICH).Semantic proximity Read ↗

Evaluation of genotoxic effects of fumagillin by cytogenetic tests in vivoSemantic proximity Read ↗

Safety evaluation of a triazine compound nitromezuril by assessing bacterial reverse mutation, sperm abnormalities, micronucleus and chromosomal aberration.Semantic proximity Read ↗

Does the 2-test in vitro genotoxicity battery of Ames plus in vitro micronucleus tests detect relevant substances that induce gene mutations in vivo?Semantic proximity Read ↗

Antimutagenic evaluation of vitamins B1, B6 and B12 in vitro and in vivo, with the Ames test.Semantic proximity Read ↗

Genotoxicity assessment of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX).Semantic proximity Read ↗

Genotoxicity assessment of an energetic propellant compound, 3-nitro-1,2,4-triazol-5-one (NTO).Semantic proximity Read ↗

Genotoxicity of quinocetone, cyadox and olaquindox in vitro and in vivo.Semantic proximity Read ↗

Tradescantia-Micronucleus (Trad-MCN) tests on 140 health-related agents.Semantic proximity Read ↗

The genotoxicity of substituted nitrobenzenes and the quantitative structure-activity relationship studies.Semantic proximity Read ↗

In Silico Methods for Chromosome Damage.Semantic proximity Read ↗

Genotoxicity test battery - An assessment of its utility in early drug development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.