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Article

Characterization of mutations induced by 300 and 320 nm UV radiation in a rat fibroblast cell line.

Mutation research - 11 Nov 1996

Akiyama N, Alexander D, Aoki Y, Noda M

Abstract excerpt

The cytotoxic and mutagenic activities of monochromatic ultraviolet light (UV) at four wavelengths (254, 290, 300 and 320 nm) were determined using a rat fibroblast cell line CREF stably infected with a retroviral vector carrying the neo and HSV-tk markers. In this system, mutations can be positively detected as acyclovir-resistant colonies. Although the action spectra for these activities closely fit some of the...

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Identifiers

PMID: 9003539
DOI: 10.1016/S0027-5107(96)00179-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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