Article
Molecular analysis of the sex hormone-binding globulin gene in the rat hypodactylous mutation (Hd).
Folia biologica - 1 Jan 2004
Liska F, Gösele C, Kren V, Hübner N, Krenová D
Abstract excerpt
Sex hormone-binding globulin or ABP/SHBG is an extracellular androgen and oestrogen carrier. In the rat, ABP/SHBG is secreted by Sertoli cells of the testis and is thought to regulate androgen bioavailability in the male reproductive tract. During ontogenesis, ABP/SHBG is expressed in many mesoderm-derived tissues, including interdigital mesenchyme of the developing autopodium. Shbg is thus a candidate for Hd,...
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