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Article

Analysis of the candidate gene NRAMP1 in the first 61 ARC National Repository families for rheumatoid arthritis.

The Journal of rheumatology - 1 Jan 1997

Shaw M A, Clayton D, Blackwell J M

Abstract excerpt

Maximum likelihood identity-by-descent (IBD) sib pair analysis using a 3 locus haplotype NRAMP1-IL8RB-VIL1, or NRAMP1 alone, provided preliminary evidence (maximum LOD score = 1.01, p = 0.024) for a gene in this region of human chromosome 2q35 contributing to susceptibility to rheumatoid arthritis (RA). Candidacy for NRAMP1 as the disease susceptibility gene was supported by a significant bias (p < 0.048) toward...

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Source

Identifiers

PMID: 9002042

Genes

ARC
VIL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of the candidate gene NRAMP1 in the first 61 ARC National Repository families for rheumatoid arthritis.PMID 9002042Read ↗

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Rheumatoid arthritis in Latin Americans enriched for Amerindian ancestry is associated with loci in chromosomes 1, 12, and 13, and the HLA class II region.Semantic proximity Read ↗

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