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Article

[Prognostic significance of p53 autoantibodies in serum of patients with breast carcinoma].

Zentralblatt fur Gynakologie - 1 Jan 1996

Huober J, Sprenger H, Costa S D, Zentgraf H, Schmid H, Kaufmann M, Bastert G

Abstract excerpt

Mutations in the p53 tumor suppressor gene are the most common genetic alterations associated with malignant tumors including breast and gynecologic carcinomas. Overexpression of p53 protein is a result of increased protein stability caused through conformationally alteration. Accumulation of mutant p53 in tumor cells may lead to a humoral immune response with development of p53 autoantibodies. In the present...

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PMID: 8999710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Prognostic significance of p53 autoantibodies in serum of patients with breast carcinoma].PMID 8999710Read ↗

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Mutant p53 protein in serum could be used as a molecular marker in human breast cancer.Semantic proximity Read ↗

[Clinical significance of p53 antibody].Semantic proximity Read ↗

p53 gene mutation, tumor p53 protein overexpression, and serum p53 autoantibody generation in patients with breast cancer.Semantic proximity Read ↗

Prognostic value of p53 molecular status in high-risk primary breast cancer.Semantic proximity Read ↗

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[Immunohistochemical detection and prognostic significance of p53 in the primary tumor of breast carcinoma patients].Semantic proximity Read ↗

[Peripheral blood mutated p53 DNA and its clinical value in human breast cancer].Semantic proximity Read ↗

The immune response to p53 in breast cancer patients is directed against immunodominant epitopes unrelated to the mutational hot spot.Semantic proximity Read ↗

Overexpression of p53 and prognosis in breast cancer.Semantic proximity Read ↗

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