Article
The teratogenic action of retinoic acid in rat congenic and recombinant inbred strains.
Folia biologica - 1 Jan 1996
Bílá V, Kren V
Abstract excerpt
The teratogenic effect of all-trans retinoic acid (RA) was tested in the system of congenic and recombinant inbred (RI) strains of the laboratory rat carrying the mutant Lx allele which determines the polydactyly-luxate syndrome. It was demonstrated that the teratogenic effect of RA is influenced...
Topics
- Animals
- Extremities
- Female
- Genotype
- Hindlimb
- Inbreeding
- Male
- Polydactyly
- Rats
- Rats, Inbred BN
- Rats, Inbred Lew
- Rats, Inbred SHR
- Recombination, Genetic
- Teratogens
- Tretinoin