The role of cell death in limb development of rats manifesting Lx allele on different genetic backgrounds.

doi:10.1076/ejom.36.3.173.4767

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Article

The role of cell death in limb development of rats manifesting Lx allele on different genetic backgrounds.

European journal of morphology - 1 Jul 1998

Sedmera D, Novotna B, Bila V, Kren V

Abstract excerpt

Control of vertebrate digital pattern is a phylogenetically old mechanism. Animal strains with abnormal digital counts are a useful model system to study tissue, cell and molecular factors involved in limb patterning. The aim of this study was to investigate rat limb morphogenesis on gestation days 13 to 16 in normodactylous, polydactylous and oligodactylous fetuses where the deviation from the normal...

Topics

Alleles
Animals
Animals, Congenic
Apoptosis
Extremities
Female
Gestational Age
Hindlimb
Male
Mesoderm
Morphogenesis
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polydactyly

Rats

Rats, Inbred BN

Rats, Inbred SHR

Rats, Mutant Strains

Rats, Wistar

Source

Open in PubMed

Identifiers

PMID: 9845263
DOI: 10.1076/ejom.36.3.173.4767

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