Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRCA1 mutations and phenotype.

Journal of cancer research and clinical oncology - 1 Jan 1997

Grade K, Höffken K, Kath R, Nothnagel A, Bender E, Scherneck S

Abstract excerpt

More than 100 mutations have been described for the breast-cancer-susceptibility gene BRCA1. The paper describes phenotypical aspects of three selected mutations located at the beginning, in the middle, and at the end of the gene. A remarkable decrease of the age of diagnosis of the mammary carcinoma is observed with increasing length of the putative gene product, combined with greater severity of the disease.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to BRCA1 gene
Share to Genes, BRCA1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Phenotype

Share to Prognosis

Share to Sequence Deletion

Source

Identifiers

PMID: 8996544
DOI: 10.1007/BF01212618

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRCA1 mutations and phenotype.PMID 8996544Read ↗

Survival and tumour characteristics of breast-cancer patients with germline mutations of BRCA1Semantic proximity Read ↗

Comparison between genotype and phenotype identifies a high-risk population carrying BRCA1 mutations.Semantic proximity Read ↗

Mutations and polymorphisms in the familial early-onset breast cancer (BRCA1) gene. Breast Cancer Information Core.Semantic proximity Read ↗

BRCA1 mutations in German breast-cancer families.Semantic proximity Read ↗

Understanding the functions of BRCA1 in the DNA-damage response.Semantic proximity Read ↗

Implication of BRCA1 gene in breast cancer.Semantic proximity Read ↗

Novel indications for BRCA1 screening using individual clinical and morphological features.Semantic proximity Read ↗

Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype-phenotype correlation.Semantic proximity Read ↗

BRCA1 in breast and ovarian cancer predisposition.Semantic proximity Read ↗

Of mice and (wo)men: genotype-phenotype correlations in BRCA1.Semantic proximity Read ↗

[Mutation BRCA1 gene in 186 breast cancer patients].Semantic proximity Read ↗

[Novel BRCA1 gene mutations in breast cancer patients from St. Petersburg].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.