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Article

Macrophage tropism of human immunodeficiency virus type 1 and utilization of the CC-CKR5 coreceptor

1 Feb 1997

Abstract excerpt

The recent identification of the CC-CKR5 beta chemokine receptor as a major cofactor for entry of macrophage-tropic isolates of human immunodeficiency virus type 1 (HIV-1) raises the question of whether macrophage tropism is determined by utilization of this chemokine receptor. We observe that in addition to macrophage-tropic isolates of clades A, B, and E, macrophage-tropic isolates of clade F also utilize the...

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PMID: 8995695
DOI: 10.1128/jvi.71.2.1657-1661.1997

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