Viral Determinants of HIV-1 Macrophage Tropism

doi:10.3390/v3112255

Article

Viral Determinants of HIV-1 Macrophage Tropism

15 Nov 2011

Abstract excerpt

Macrophages are important target cells for HIV-1 infection that play significant roles in the maintenance of viral reservoirs and other aspects of pathogenesis. Understanding the determinants of HIV-1 tropism for macrophages will inform HIV-1 control and eradication strategies. Tropism for macrophages is both qualitative (infection or not) and quantitative (replication capacity). For example many R5 HIV-1...

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