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Article

Active site mutants implicate key residues for control of color and light cycle kinetics of photoactive yellow protein.

Biochemistry - 7 Jan 1997

Genick U K, Devanathan S, Meyer T E, Canestrelli I L, Williams E, Cusanovich M A, Tollin G, Getzoff E D

Abstract excerpt

To understand how the protein and chromophore components of a light-sensing protein interact to create a light cycle, we performed time-resolved spectroscopy on site-directed mutants of photoactive yellow protein (PYP). Recently determined crystallographic structures of PYP in the ground and colorless I2 states allowed us to design mutants and to study their photosensing properties at the atomic level. We...

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Identifiers

PMID: 8993312
DOI: 10.1021/bi9622884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Active site mutants implicate key residues for control of color and light cycle kinetics of photoactive yellow protein.PMID 8993312Read ↗

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