Article
A structural pathway for signaling in the E46Q mutant of photoactive yellow protein.
Structure (London, England : 1993) - 1 Jan 2005
Rajagopal Sudarshan, Anderson Spencer, Srajer Vukica, Schmidt Marius, Pahl Reinhard, Moffat Keith
Abstract excerpt
In the bacterial photoreceptor photoactive yellow protein (PYP), absorption of blue light by its chromophore leads to a conformational change in the protein associated with differential signaling activity, as it executes a reversible photocycle. Time-resolved Laue crystallography allows structural snapshots (as short as 150 ps) of high crystallographic resolution (approximately 1.6 A) to be taken of a protein as...
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