Article
Organ variation in the mutagenicity of ethylnitrosourea in Muta mouse: results of the collaborative study on the transgenic mutation assay by JEMS/MMS. The Collaborative Study Group for the Transgenic Mouse Mutation Assay Mammalian Mutagenesis Study Group of the Environmental Mutagen Society of Japan.
Environmental and molecular mutagenesis - 1 Jan 1996
Abstract excerpt
A collaborative study of the transgenic mouse mutation assay was performed by a subgroup of the Mammalian Mutagenesis Study Group (MMS), which is a suborganization of the Environmental Mutagen Society of Japan (JEMS). Twenty-six laboratories participated in this collaboration, and ethylnitrosourea (ENU) mutagenesis was studied in eight organs of lacZ transgenic mice (Muta Mouse)-liver, spleen, bone marrow, brain,...
Topics
- Animals
- Ethylnitrosourea
- Male
- Mice
- Mice, Transgenic
- Mutagenicity Tests
- Mutagens
- Mutation
- Reproducibility of Results
- Tissue Distribution
- beta-Galactosidase