Article
Effects of interleukins on Crouzon fibroblast phenotype in vitro. Release of cytokines and IL-6 mRNA expression.
Cytokine - 1 Oct 1996
Bodo M, Carinci F, Baroni T, Becchetti E, Giammarioli M, Bellucci C, Pezzetti F, Evangelisti R, Carinci P
Abstract excerpt
In Crouzon's syndrome, the cranial morphogenic processes are altered due to the early fusion of the facial and basal cranial bones. Evidence that Crouzon fibroblasts have an altered phenotype which is modulated by interleukin 1 (IL-1) and interleukin 6 (IL-6) is provided. [3H]Thymidine incorporation and cell count studies showed that Crouzon fibroblasts have an accelerated proliferation rate. [3H]Glucosamine...
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