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Article

Proteome changes in ovarian epithelial cells derived from women with BRCA1 mutations and family histories of cancer.

Molecular & cellular proteomics : MCP - 1 Feb 2005

Smith-Beckerman Diana M, Fung Kit W, Williams Katherine E, Auersperg Nelly, Godwin Andrew K, Burlingame Alma L

Abstract excerpt

Malignant transformation of the ovarian surface epithelium (OSE) accounts for most ovarian carcinoma. Detection of preneoplastic changes in the OSE leading to overt malignancy is important in prevention and management of ovarian cancer. We identified OSE proteins with altered expression derived from women with a family history (FH) of ovarian and/or breast cancer and mutations in the BRCA1 tumor suppressor gene....

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Source

Identifiers

PMID: 15591324
DOI: 10.1074/mcp.M400157-MCP200

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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