Article
The impact of HLA-DRB1*0405 on disease severity in Korean patients with seropositive rheumatoid arthritis.
British journal of rheumatology - 1 Apr 1997
Kim H Y, Min J K, Yang H I, Park S H, Hong Y S, Jee W H, Lee S H, Cho C S, Kim T G, Han H
Abstract excerpt
Many reports have described HLA-DRB1 genes as having an influence on disease severity and susceptibility in rheumatoid arthritis (RA). Studies were undertaken to define the effect of RA-associated alleles on disease severity in Korean patients with seropositive RA. The results indicate that the most common RA susceptibility allele, HLA-DRB1*0405, is significantly associated with bony erosion, joint deformity and...
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