Article
Temperature sensitivity of some mutants of the lutropin/choriogonadotropin receptor.
Endocrinology - 1 Jan 1997
Jaquette J, Segaloff D L
Abstract excerpt
The lutropin/choriogonadotropin receptor (LHR) is a G protein-coupled receptor central to reproductive physiology. In addition to the complex structure formed by seven membrane-spanning helices, this receptor also contains a large amino-terminal domain whose tertiary structure is unknown. Many mutations of this receptor result in partial or complete intracellular retention of the mutant, regardless of whether the...
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