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Article

A novel SP-1 site in the human interleukin-1 beta promoter confers preferential transcriptional activity in keratinocytes.

European journal of immunology - 1 Dec 1996

Husmann M, Jehnichen P, Jahn B, Schlosshan D, Romahn E, Marx J

Abstract excerpt

To investigate the mechanisms of transcriptional activation of interleukin-1beta (IL-1beta) in non-monocytic cells, we constructed a series of reporter plasmids with the bacterial chloramphenicol acetyltransferase gene linked to various parts of the human IL-1beta promoter and performed transient transfection experiments. We identified a promoter segment that activates transcription most efficiently in...

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Source

Identifiers

PMID: 8977297
DOI: 10.1002/eji.1830261228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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