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Article

Effects of differential expression of the 49-kilodalton exoenzyme S by Pseudomonas aeruginosa on cultured eukaryotic cells.

Infection and immunity - 1 Jan 1997

Olson J C, McGuffie E M, Frank D W

Abstract excerpt

Production of the ADP-ribosylating enzyme exoenzyme S (ExoS) by Pseudomonas aeruginosa has been associated with increased virulence. Previous studies, however, have been unable to confirm an effect of soluble ExoS in cell culture or animal model systems. To determine if bacteria must come in contact with target cells in order for an effect of ExoS to be observed, coculture systems were developed to compare the...

Topics

ADP Ribose Transferases
Bacterial Proteins
Bacterial Toxins
Cell Communication
Cell Survival
Cells, Cultured
Culture Techniques
Eukaryotic Cells
Mutation
Poly(ADP-ribose) Polymerases
Pseudomonas aeruginosa

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Deletion

Solubility

Toxicity Tests

Source

Open in PubMed Open full text

Identifiers

PMID: 8975919
DOI: 10.1128/iai.65.1.248-256.1997
PMCID: PMC174583

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Effects of differential expression of the 49-kilodalton exoenzyme S by Pseudomonas aeruginosa on cultured eukaryotic cells.PMID 8975919Read ↗

Regulation of ExoS production and secretion by Pseudomonas aeruginosa in response to tissue culture conditions.Semantic proximity Read ↗

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