Article
Regulation of ExoS production and secretion by Pseudomonas aeruginosa in response to tissue culture conditions.
Infection and immunity - 1 Feb 1999
Vallis A J, Yahr T L, Barbieri J T, Frank D W
Abstract excerpt
This study was initiated to characterize the regulation and secretion of ExoS by Pseudomonas aeruginosa during contact with eukaryotic cells. The production of ExoS was monitored by a sensitive ADP-ribosyltransferase activity assay, and specific activities were calculated for supernatant and cell-associated fractions. Time course analysis indicated that ExoS was produced after a lag period, suggesting that...
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