Article
Pat1: a topoisomerase II-associated protein required for faithful chromosome transmission in Saccharomyces cerevisiae.
Nucleic acids research - 1 Dec 1996
Wang X, Watt P M, Louis E J, Borts R H, Hickson I D
Abstract excerpt
Saccharomyces cerevisiae top2 mutants deficient in topoisomerase II activity are defective in chromosome segregation during both mitotic and meiotic cell divisions. To identify proteins that act in concert with topoisomerase II during chromosome segregation in S.cerevisiae, we have used a two-hyb...
Topics
- Binding Sites
- Cell Division
- Chromosomes, Fungal
- Cloning, Molecular
- DNA Topoisomerases, Type II
- DNA, Fungal
- DNA-Binding Proteins
- Gene Deletion
- Gene Expression
- Leucine
- Meiosis
- Mitosis
- Mutation
- Phenotype
- RNA-Binding Proteins
- Recombinant Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins