Article
Molecular genetic analysis of glucocorticoid signaling during mouse development.
Steroids - 1 Jan 1995
Cole T J, Blendy J A, Monaghan A P, Schmid W, Aguzzi A, Schütz G
Abstract excerpt
Glucocorticoids are important in a number of developmental processes in mammals around birth. The pathway of gluconeogenesis is activated in liver shortly after birth due to the combined effects of glucocorticoids and glucagon. We have defined the essential cis-regulatory elements directing hormone-dependent liver-specific expression of the gene for tyrosine aminotransferase, a key gluconeogenic enzyme. The...
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