Article
Variants able to cause growth hormone deficiency syndrome are present within the disease-nil WE strain of lymphocytic choriomeningitis virus.
Journal of virology - 1 Dec 1996
Buesa-Gomez J, Teng M N, Oldstone C E, Oldstone M B, de la Torre J C
Abstract excerpt
Persistent infection of C3H/St mice with lymphocytic choriomeningitis virus (LCMV) strain Armstrong leads to disordered growth and hypoglycemia. Both host and viral determinants contribute to this growth hormone (GH) deficiency syndrome (GHDS). Development of the GHDS correlates with the virus's...
Topics
- Animals
- Antigens, Viral
- Brain
- Genetic Variation
- Glyceraldehyde-3-Phosphate Dehydrogenases
- Growth Disorders
- Growth Hormone
- Hypoglycemia
- Liver
- Lymphocytic choriomeningitis virus
- Mice
- Mice, Inbred C3H
- Pituitary Gland
- Syndrome