Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The interaction of a type A retroviral particle and class II human leukocyte antigen susceptibility genes in the pathogenesis of Graves' disease.

The Journal of clinical endocrinology and metabolism - 1 Jun 1996

Jaspan J B, Sullivan K, Garry R F, Lopez M, Wolfe M, Clejan S, Yan C, Tenenbaum S, Sander D M, Ahmed B, Bryer-Ash M

Abstract excerpt

We have previously reported that over 85% of patients with Graves' disease have detectable serum antibodies against a human intracisternal type A retroviral particle (HIAP), which are not present in age- and gender-matched controls, suggesting a role for HIAP in triggering the autoimmune process leading to Graves' disease. To investigate the interaction of this viral particle with genetic factors, 35 members of 3...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Viral
Share to Autoantibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Haplotypes

Share to Histocompatibility Antigens Class II

Share to Retroviridae

Share to Virion

Source

Identifiers

PMID: 8964863
DOI: 10.1210/jcem.81.6.8964863

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The interaction of a type A retroviral particle and class II human leukocyte antigen susceptibility genes in the pathogenesis of Graves' disease.PMID 8964863Read ↗

The epidemiology of Graves' disease: evidence of a genetic and an environmental contribution.Semantic proximity Read ↗

Genetic susceptibility to Grave's disease.Semantic proximity Read ↗

Role of genetics and epigenetics in Graves' orbitopathy.Semantic proximity Read ↗

Susceptibility genes in Graves' ophthalmopathy: searching for a needle in a haystack?Semantic proximity Read ↗

Risk factors for development or deterioration of Graves' ophthalmopathy.Semantic proximity Read ↗

Limited genetic susceptibility to severe Graves' ophthalmopathy: no role for CTLA-4 but evidence for an environmental etiology.Semantic proximity Read ↗

Limited Genetic Overlap Between Overt Hashimoto's Thyroiditis and Graves' Disease in Twins: A Population-based Study.Semantic proximity Read ↗

Genetic determinants of Graves disease.Semantic proximity Read ↗

Herpesvirus type 7 infection may play an important role in individuals with a genetic profile of susceptibility to Graves' disease.Semantic proximity Read ↗

Genetic determinants of antithyroid drug-induced agranulocytosis by human leukocyte antigen genotyping and genome-wide association study.Semantic proximity Read ↗

Pathogenesis of Graves' orbitopathy: a 2010 update.Semantic proximity Read ↗

Familial Risk of Graves Disease Among First-Degree Relatives and Interaction With Smoking: A Population-Based Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.