Article
Limited Genetic Overlap Between Overt Hashimoto's Thyroiditis and Graves' Disease in Twins: A Population-based Study.
The Journal of clinical endocrinology and metabolism - 25 Mar 2021
Skov Jakob, Calissendorff Jan, Eriksson Daniel, Magnusson Patrik, Kämpe Olle, Bensing Sophie, Kuja-Halkola Ralf
Abstract excerpt
CONTEXT: Hashimoto's thyroiditis (HT) and Graves' disease (GD) are known to coaggregate in families, but the magnitude and nature of a shared etiology is unknown. OBJECTIVES: To estimate the shared genetic influence on overt HT and GD and to examine if the heritability differs between men and women. DESIGN, SETTING, AND PATIENTS: We used national health registries to identify cases of HT and GD in a cohort of 110...
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